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Wnt Pathway Targeted Therapy in GI Cancers: Integrating Benchside Insights with Bedside Applications

2024-12-11

Abstract excerpt

The Wnt signaling pathway is critical in the onset and progression of gastrointestinal (GI) cancers. Anomalies in this pathway, often stemming from mutations in critical components such as adenomatous polyposis coli (APC) or β-catenin, lead to uncontrolled cell proliferation and survival. In the case of colorectal cancer, dysregulation of the Wnt pathway drives tumor initiation and growth. Similarly, aberrant Wnt...

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Literature Corpus work
c3745de5-0f80-5070-b520-ad953c0e48b5
DOI
10.20944/preprints202412.0995.v1
Open publication

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Wnt Pathway Targeted Therapy in GI Cancers: Integrating Benchside Insights with Bedside ApplicationsDOI 10.20944/preprints202412.0995.v1
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