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Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

14 Jul 2022

Abstract excerpt

BACKGROUND: The Wnt signaling pathway is a complex network of protein interactions that functions most commonly in embryonic development and cancer, but is also involved in normal physiological processes in adults. The canonical Wnt signaling pathway regulates cell pluripotency and determines the differentiation fate of cells during development. The canonical Wnt signaling pathway (also known as the Wnt/β-catenin...

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PMID: 35836256
DOI: 10.1186/s12943-022-01616-7

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