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Article

The potential of targeting Wnt/β-catenin in colon cancer

5 Apr 2014

Abstract excerpt

The Wnt signaling pathway controls several cell processes, such as motility and proliferation during embryonic development. Wnt signaling is also involved in the maintenance of potency and the induction of differentiation in stem cells. Aberrant Wnt signaling is implicated in several cancer types. Particularly in colorectal cancer (CRC), the Wnt-β-catenin signaling cascade is at the center of the carcinogenesis,...

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Share to Cancer-related gene regulation
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Share to Wnt/β-catenin signaling in development and cancer

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PMID: 24702624
DOI: 10.1517/14728222.2014.906580

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