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Article

Multi-trait Analysis of GWAS Expands Eosinophilic Esophagitis Genetic Susceptibility and Polygenic Risk Scores

2025-07-18

Abstract excerpt

<title>Abstract</title> <p> Atopic diseases, including eosinophilic esophagitis (EoE), are driven in part by genetic susceptibility. We performed a genome-wide association study (GWAS) of 1,757 EoE and 14,467 population controls, identifying 11 independent genetic risk variants spanning 8 EoE risk loci (p < 5x10 <sup>− 8</sup> ), including 3 new loci. A multi-trait analysis of GWAS (MTAG) of EoE and other atop...

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Literature Corpus work
c354c0f2-ac7c-5fb1-9048-e09c1b1327b5
DOI
10.21203/rs.3.rs-6630283/v2
Open publication

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Multi-trait Analysis of GWAS Expands Eosinophilic Esophagitis Genetic Susceptibility and Polygenic Risk ScoresDOI 10.21203/rs.3.rs-6630283/v2
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