Clinical heterogeneity and endotype stratification in eosinophilic esophagitis.

Abstract excerpt

Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disease marked by esophageal dysfunction and eosinophilic inflammation, with significant variability in presentation, course, and treatment response. Although patients are diagnosed using the same criteria, they exhibit a range of characteristics with varying age at onset, symptoms, endoscopic appearance, treatment response, and progression...

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