Article

Dynamic changes in clonal architecture during disease progression in follicular lymphoma

2017-09-11

Abstract excerpt

<h4>ABSTRACT</h4> Follicular lymphoma (FL) is typically a slow growing cancer that can be effectively treated. Some patients undergo transformation to diffuse large B cell lymphoma (DLBCL), which is frequently resistant to chemotherapy and is generally fatal. Targeted sequencing of DNA and RNA was applied to identify mutations and transcriptional changes that accompanied transformation in a cohort of 16 patients,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c32a5b4d-f2ea-548d-8078-55a3b5ff7c1c
DOI: 10.1101/181792

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic changes in clonal architecture during disease progression in follicular lymphomaDOI 10.1101/181792Read

Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study.Semantic proximity Read

From genetics to the clinic: a translational perspective on follicular lymphoma.Semantic proximity Read

Genetics of follicular lymphoma transformation.Semantic proximity Read

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma.Semantic proximity Read

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma.Semantic proximity Read

Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma.Semantic proximity Read

Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma.Semantic proximity Read

Integrated single cell analysis reveals co-evolution of malignant B cells and the tumor microenvironment in transformed follicular lymphomaSemantic proximity Read

Molecular subclusters of follicular lymphoma: a report from the United Kingdom's Haematological Malignancy Research Network.Semantic proximity Read

Genomic landscape of follicular lymphoma across a wide spectrum of clinical behaviors.Semantic proximity Read

Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphomaSemantic proximity Read

Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns.Semantic proximity Read