Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma.

doi:10.1038/s41408-024-01124-5

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Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma.

Blood cancer journal - 27 Aug 2024

Bai Baoyan, Wise Jillian F, Vodák Daniel, Nakken Sigve, Sharma Ankush, Blaker Yngvild Nuvin, Brodtkorb Marianne, Hilden Vera, Trøen Gunhild, Ren Weicheng, Lorenz Susanne, Lawrence Michael S, Myklebost Ola, Kimby Eva, Pan-Hammarström Qiang, Steen Chloé B, Meza-Zepeda Leonardo A, Beiske Klaus, Smeland Erlend B, Hovig Eivind, Lingjærde Ole Christian, Holte Harald, Myklebust June Helen

Abstract excerpt

Follicular lymphoma (FL) is the most common indolent type of B-cell non-Hodgkin lymphoma. Advances in treatment have improved overall survival, but early relapse or transformation to aggressive disease is associated with inferior outcome. To identify early genetic events and track tumor clonal evolution, we performed multi-omics analysis of 94 longitudinal biopsies from 44 FL patients; 22 with transformation...

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PMID: 39191762
DOI: 10.1038/s41408-024-01124-5
PMCID: PMC11350178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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