Article
Molecular subclusters of follicular lymphoma: a report from the United Kingdom's Haematological Malignancy Research Network.
Blood advances - 8 Nov 2022
Crouch Simon, Painter Daniel, Barrans Sharon L, Roman Eve, Beer Philip A, Cooke Susanna L, Glover Paul, Van Hoppe Suzan J L, Webster Nichola, Lacy Stuart E, Ruiz Camilo, Campbell Peter J, Hodson Daniel J, Patmore Russell, Burton Cathy, Smith Alexandra, Tooze Reuben M
Abstract excerpt
Follicular lymphoma (FL) is morphologically and clinically diverse, with mutations in epigenetic regulators alongside t(14;18) identified as disease-initiating events. Identification of additional mutational entities confirms this cancer's heterogeneity, but whether mutational data can be resolved into mechanistically distinct subsets remains an open question. Targeted sequencing was applied to an unselected...
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