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Integrating transcriptome-wide association study and mRNA expression profile identified sensitive genes related to hand osteoarthritis

2020-09-30

Abstract excerpt

<h4>Background: </h4> Osteoarthritis (OA) is a common skeletal system disease which proven partly related to genetic factors. The hand is a frequently affected part, which seriously affects the quality of life. But pathogenesis mechanism of hand osteoarthritis (hand OA) is still elusive. Methods The Genome-wide association study (GWAS)summary of hand OA was derived from the UK Biobank, which contains 452,264 Whit...

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Literature Corpus work
c2f61896-d7e6-5f69-8877-413b724ae751
DOI
10.21203/rs.3.rs-81386/v1
Open publication

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Integrating transcriptome-wide association study and mRNA expression profile identified sensitive genes related to hand osteoarthritisDOI 10.21203/rs.3.rs-81386/v1
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