Article

Integrating the analysis of transcriptome-wide association study and gene expression profile to identify genes associated with spondyloarthritis

2021-10-26

Abstract excerpt

<h4>Background: </h4> Spondyloarthritis(SpA) is a group of multi-factorial bone diseases influenced by genetic factors, environment and lifestyles. However, the genetic and pathogenic mechanism of SpA is still elusive. Methods Firstly, the tissue-specific transcriptome-wide association study (TWAS) of SpA was performed by utilizing the genome-wide association study (GWAS, including 3966 SpA patients and 452264 co...

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Literature Corpus work: d223797a-1b4e-5aaa-b009-f6a596fdbc74
DOI: 10.21203/rs.3.rs-936677/v1

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