Article
Identification of gene expression profiles and key genes in subchondral bone of osteoarthritis using weighted gene coexpression network analysis.
Journal of cellular biochemistry - 1 Sept 2018
Guo Sheng-Min, Wang Jian-Xiong, Li Jin, Xu Fang-Yuan, Wei Quan, Wang Hai-Ming, Huang Hou-Qiang, Zheng Si-Lin, Xie Yu-Jie, Zhang Chi
Abstract excerpt
Osteoarthritis (OA) significantly influences the quality life of people around the world. It is urgent to find an effective way to understand the genetic etiology of OA. We used weighted gene coexpression network analysis (WGCNA) to explore the key genes involved in the subchondral bone pathological process of OA. Fifty gene expression profiles of GSE51588 were downloaded from the Gene Expression Omnibus...
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