Article

Complement C5 is not critical for the formation of sub-RPE deposits in <i>Efemp1</i> mutant mice

2020-12-16

Abstract excerpt

<h4>ABSTRACT</h4> The complement system plays a role in the formation of sub-retinal pigment epithelial (RPE) deposits in early stages of age-related macular degeneration (AMD). But the specific mechanisms that connect complement activation and deposit formation in AMD patients are unknown, which limits the development of efficient therapies to reduce or stop disease progression. We have previously demonstrated t...

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Literature Corpus work: c2e8096c-1f30-5a3b-9b53-06df81e2452a
DOI: 10.1101/2020.12.16.423072

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