Article

Roquin1 inhibits the proliferation of breast cancer cells by inducing G1/S cell cycle arrest via selectively destabilizing the mRNAs of cell cycle–promoting genes

2020-11-11

Abstract excerpt

<h4>Background: </h4> Dysregulation of cell cycle progression is one of the common features of human cancer cells, however, its mechanism remains unclear. This study aims to clarify the role and the underlying mechanisms of Roquin1 in cell cycle arrest induction in breast cancer. <h4>Methods: </h4>: Public cancer databases were analyzed to identify the expression pattern of Roquin1 in human breast cancers and the...

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Literature Corpus work: eb5ddfff-aa04-51f5-a5dc-054e63c66ab9
DOI: 10.21203/rs.3.rs-53499/v3

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