Article
Molecular control of Tfh-cell differentiation by Roquin family proteins.
Immunological reviews - 1 May 2013
Heissmeyer Vigo, Vogel Katharina U
Abstract excerpt
Post-transcriptional gene regulation by RNA-binding proteins is a fast and effective way to adapt gene expression and change cellular responses. These trans-acting factors have been involved in a number of cell fate decisions, and their mutation is often associated with the development of disease. The RNA-binding protein Roquin-1 has been found to be crucial in the maintenance of peripheral tolerance and the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
