Article
Fluctuating fitness shapes the clone size distribution of immune repertoires
2015-07-05
Abstract excerpt
The adaptive immune system relies on the diversity of receptors expressed on the surface of B and T-cells to protect the organism from a vast amount of pathogenic threats. The proliferation and degradation dynamics of different cell types (B cells, T cells, naive, memory) is governed by a variety of antigenic and environmental signals, yet the observed clone sizes follow a universal power law distribution. Guided...
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Identifiers and source
- Literature Corpus work
- c2b96329-c98d-5690-9db7-a7c1a80fa7ea
- DOI
- 10.1101/021923