Article
Foamy virus vector integration and application in gene therapy
2015-01-01
Abstract excerpt
Foamy viruses (FVs) are unique ancient retroviruses that infect all non-human primates, but do not cause disease. We aimed to understand the FV pre-integration complex by isolating it from infected cells and characterising its protein constituents. Using a PCR to quantify integration in infected cells, we determined that integration occurs from 10 hours post-transduction. In synchronised cells, the peak of integra...
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Identifiers and source
- Literature Corpus work
- c29c8c1f-b4ed-5017-a0d4-6189978b4e61
- DOI
- 10.25560/50704