Improved Primate Foamy Virus Vectors and Packaging Constructs

Abstract excerpt

Foamy virus (FV) vectors that have minimal cis-acting sequences and are devoid of residual viral gene expression were constructed and analyzed by using a packaging system based on transient cotransfection of vector and different packaging plasmids. Previous studies indicated (i) that FV gag gene expression requires the presence of the R region of the long terminal repeat and (ii) that RNA from packaging...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to HIV Research and Treatment
• Share to Virology and Viral Diseases
• Share to Virus-based gene therapy research