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Article

Properties of human foamy virus relevant to its development as a vector for gene therapy

1 Aug 1999

Abstract excerpt

The Spumaviridae (foamy viruses) are increasingly being considered as potential vectors for gene therapy, yet little has been documented of their basic cell biology. This study demonstrates that human foamy virus (HFV) has a broad tropism and that the receptor for HFV is expressed not only on many mammalian, but on avian and reptilian cells. Receptor interference assays using an envelope-expressing cell line and...

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PMID: 10466797
DOI: 10.1099/0022-1317-80-8-2003

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