Article
MRI-assessed locus coeruleus contrast and functional response are not associated in young and late middle-aged individuals
2023-01-18
Abstract excerpt
The brainstem locus coeruleus (LC) influences a broad range of brain processes, including cognition. The so-called LC contrast is an accepted marker of the integrity of the LC that consists of a local hyperintensity on specific Magnetic Resonance Imaging (MRI) structural images. The small size of the LC has, however, rendered its functional characterization difficult in humans, including in aging. A full character...
Topics
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- Advanced Neuroimaging Techniques and Applications
- Alzheimer's disease research and treatments
- Amino Acid Enzymes and Metabolism
- Dementia and Cognitive Impairment Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological disorders and treatments
- Neuroscience and Neuropharmacology Research
- Parkinson's Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- c27cbb00-5034-5e63-92ea-fa6b0b34fff0
- DOI
- 10.1101/2023.01.16.524213
