Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan study

1 Jun 2024

Abstract excerpt

The locus coeruleus-norepinephrine system plays a key role in supporting brain health along the lifespan, notably through its modulatory effects on neuroinflammation. Using ultra-high field diffusion magnetic resonance imaging, we examined whether microstructural properties (neurite density index and orientation dispersion index) in the locus coeruleus were related to those in cortical and subcortical regions,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Neuroimaging Techniques and Applications
Share to Alzheimer's disease research and treatments
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38904081
DOI: 10.1093/cercor/bhae261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microstructural associations between locus coeruleus, cortical, and subcortical regions are modulated by astrocyte reactivity: a 7T MRI adult lifespan studyPMID 38904081Read ↗

Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseasesSemantic proximity Read ↗

Periventricular diffusion gradient of normal-appearing white matter and its transcriptional signatures in normal aging and multiple neurological diseasesSemantic proximity Read ↗

Impact of Alzheimer’s disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleusSemantic proximity Read ↗

Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer’s diseaseSemantic proximity Read ↗

Developmental changes in diffusion markers of neurite vary across the hippocampus and covary with the cellular composition of hippocampal tissueSemantic proximity Read ↗

Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's diseaseSemantic proximity Read ↗

Fully automated segmentation of the locus coeruleus: application to assess the effects of age, sex and educationSemantic proximity Read ↗

Associations among locus coeruleus catecholamines, tau pathology, and memory in agingSemantic proximity Read ↗

Adipokines contribute to central-obesity related reductions in myelin-sensitive MRI indices in the fornixSemantic proximity Read ↗

Early alteration of the locus coeruleus in phenotypic variants of Alzheimer’s diseaseSemantic proximity Read ↗

Vulnerability of the locus coeruleus-entorhinal cortex white matter tract in autosomal dominant Alzheimer's disease.Semantic proximity Read ↗

Fully Automated MRI-based Analysis of the Locus Coeruleus in Aging and Alzheimer’s Disease Dementia using ELSI-NetSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.