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Longitudinal decline in striatal dopamine transporter binding in Parkinson’s disease: Associations with apathy and anhedonia

2022-07-12

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Motivational symptoms such as apathy and anhedonia are common in Parkinson’s disease, respond poorly to treatment, and have been hypothesised to share underlying neural mechanisms. Striatal dopaminergic dysfunction is considered central to motivational symptoms in Parkinson’s disease, but the association has never been examined longitudinally. We investigated whether the progre...

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Literature Corpus work
c275bff5-6c5f-5ef3-9bf6-aaeefc4904b2
DOI
10.1101/2022.07.11.22277484
Open publication

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Longitudinal decline in striatal dopamine transporter binding in Parkinson’s disease: Associations with apathy and anhedoniaDOI 10.1101/2022.07.11.22277484
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