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Clinically probable RBD is an early predictor of malignant non-motor Parkinson’s disease phenotypes

29 Jan 2025

Abstract excerpt

Non-motor symptoms (NMS) in Parkinson’s disease (PD) significantly impact quality of life, especially in later stages. REM sleep behavior disorder (RBD) affects approximately 42% of all PD patients and frequently precedes motor PD symptoms. RBD is linked to increased rates of depression and cognitive decline. This study explores how early RBD can predict the development of NMS profiles in patients, comparing...

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Neurological disorders and treatments
Parkinson's Disease Mechanisms and Treatments
RNA regulation and disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39875387
DOI: 10.1038/s41531-025-00874-8

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