Article

ARID1A orchestrates the activity of FOXA1 and AP-2 transcription factors in lobular breast cancer cells

2026-06-11

Abstract excerpt

Mutations in components of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin-remodelling complex are among the most common genetic alterations in human cancers, yet their functional consequences are difficult to predict as they are highly context-dependent. ARID1A, a core subunit of the canonical BAF complex, is the most frequently mutated SWI/SNF gene and is recurrently altered in breast cancer, with a notab...

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Literature Corpus work: c2737edc-7a9f-5ad1-a829-f595cfcf1d37
DOI: 10.64898/2026.06.08.730919

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