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Article

ARID1A mutations in cancer: another epigenetic tumor suppressor?

Cancer discovery - 1 Jan 2013

Wu Jennifer N, Roberts Charles W M

Abstract excerpt

UNLABELLED: Although disordered chromatin organization has long been recognized as a feature of cancer, the molecular underpinnings of chromatin structure, epigenetic regulation, and their relationships to transcription are only beginning to be understood. Cancer genome sequencing studies have revealed a novel theme: frequent mutation of epigenetic regulators. Among these, the ARID1A/BAF250A subunit of the...

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Identifiers

PMID: 23208470
DOI: 10.1158/2159-8290.CD-12-0361
PMCID: PMC3546152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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