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Article

The Role of ARID1A in Tumors: Tumor Initiation or Tumor Suppression?

4 Oct 2021

Abstract excerpt

Genes encoding subunits of SWItch/Sucrose Non-Fermenting (SWI/SNF) chromatin remodeling complexes are collectively mutated in 20% of all human cancers, among which the AT-rich interacting domain−containing protein 1A (ARID1A, also known as BAF250a, B120, C1orf4, Osa1) that encodes protein ARID1A is the most frequently mutated, and mutations in ARID1A have been found in various types of cancer. ARID1A is thought...

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Identifiers

PMID: 34671561
DOI: 10.3389/fonc.2021.745187

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