Article

Resolving RH and GYP hybrid alleles while accessing the entire blood group genome with Nanopore adaptive sampling

2025-06-11

Abstract excerpt

Adaptive sampling (AS), a computational enrichment method developed for Oxford Nanopore Technologies sequencing platforms, offers a promising advance in molecular blood group diagnostics. By leveraging long-read sequencing, AS has the potential to accurately resolve complex structural variants in the RH and MNS blood group systems, while characterizing the entire blood group genome. In this study, we evaluated the...

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Literature Corpus work: c26f0994-05bb-5e13-870d-d7075eaef72f
DOI: 10.1101/2025.06.10.25328638

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