Calling for diversity: improving transfusion safety through high-throughput blood group microarray genotyping

Abstract excerpt

<h4>ABSTRACT</h4> Blood transfusions, conducted between donors compatible in their red blood cell (RBC) antigens, play a life-saving role in transfusion medicine. Genetic differences at blood group loci between ethnicities result in diversity and altered frequency of RBC antigens that need to be considered in blood transfusion. Consequently, comprehensive, and accurate blood group antigen typing is especially rele...

Topics

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• Blood Group Antigens
• Blood Grouping and Crossmatching
• Blood groups and transfusion
• Erythrocytes
• Genetic Variation
• Genotype
• Genotyping Techniques
• High-Throughput Nucleotide Sequencing

Identifiers and source

Literature Corpus work

741af40f-29ad-5cae-b578-437f1c4aa5ca

DOI

10.1101/2023.12.15.23299980