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Article

Genetic dissection of femoral and tibial microarchitecture

2019-01-04

Abstract excerpt

Our understanding of the genetic control of bone has relied almost exclusively on estimates of bone mineral density. In contrast, here we have used high-resolution x-ray tomography (8 μm isotropic voxels) to measure femoral and tibial components across a set of ~600 mice belonging to 60 diverse BXD strains of mice. We computed heritabilities of 25 cortical and trabecular compartments. Males and females have well m...

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Literature Corpus work
3ca60462-3546-542d-a469-82d4962eab4a
DOI
10.1101/512103
Open publication

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Genetic dissection of femoral and tibial microarchitectureDOI 10.1101/512103
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