Article
Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture.
BMC genomics - 26 Nov 2015
Levy Roei, Mott Richard F, Iraqi Fuad A, Gabet Yankel
Abstract excerpt
BACKGROUND: The microstructure of trabecular bone is a composite trait governed by a complex interaction of multiple genetic determinants. Identifying these genetic factors should significantly improve our ability to predict of osteoporosis and its associated risks. Genetic mapping using collaborative cross mice (CC), a genetically diverse recombinant inbred mouse reference panel, offers a powerful tool to...
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