Article

Iron export and lipid droplets shield deep-diving elephant seal cells from lipid peroxidation

2026-08-15

Abstract excerpt

Elephant seals are remarkable breath-hold divers, capable of remaining submerged for up to two hours during diving bouts. These dives entail repeated, extreme hypoxia/reoxygenation events that would induce severe lipid peroxidation and tissue dysfunction in most mammals. Here, we show that primary vascular endothelial cells derived from elephant seals possess an intrinsic resistance to lipid peroxidation. Comparat...

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Literature Corpus work: c258b749-93a4-570a-9df4-b199caba3ea0
DOI: 10.64898/2026.08.10.744012

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