Article

Phthalate Exposure Induces Inflammatory Signaling and Suppresses Mitochondrial Function in Marine Mammal and Human Cells

2026-02-11

Abstract excerpt

<h4>ABSTRACT</h4> This study investigated the transcriptional and bioenergetic responses to monoethylhexyl phthalate (MEHP) in primary fibroblasts derived from northern elephant seals ( Mirounga angustirostris ), common dolphins ( Delphinus delphis ), and humans, using RNA-seq, extracellular flux assays, and high-resolution microscopy of the mitochondrial reticulum. MEHP exposure did not induce cytotoxicity but...

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Literature Corpus work: ff6f58c7-b7c7-5a7f-830c-673b645e4347
DOI: 10.64898/2026.02.09.704935

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