Article
Naked mole rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles
2023-05-22
Abstract excerpt
The naked mole-rat Heterocephalus glaber is a eusocial mammal exhibiting extreme longevity (37-year lifespan), extraordinary resistance to hypoxia and absence of cardiovascular disease. To identify the mechanisms behind these exceptional traits, RNAseq and metabolomics of cardiac tissue from naked mole-rats was compared to other African mole-rat genera. We identified metabolic and genetic adaptations unique to na...
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Identifiers and source
- Literature Corpus work
- af2dfc6d-4b93-553c-8cc3-dfc2c7252eb5
- DOI
- 10.1101/2023.05.19.541451