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Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are key features of alpacas resolving MERS-CoV infection

2020-11-25

Abstract excerpt

<h4>ABSTRACT</h4> While MERS-CoV (Middle East respiratory syndrome Coronavirus) provokes a lethal disease in humans, camelids, the main virus reservoir, are asymptomatic carriers, suggesting a crucial role for innate immune responses in controlling the infection. Experimentally infected camelids clear infectious virus within one week and mount an effective adaptive immune response. Here, transcription of immune r...

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Literature Corpus work
c22e6770-722b-5c31-aa0a-0bbb5b32f507
DOI
10.1101/2020.11.23.395301
Open publication

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Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are key features of alpacas resolving MERS-CoV infectionDOI 10.1101/2020.11.23.395301
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