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Long-read RNA-seq resolves isoform-level and context-specific regulatory architecture of complex traits in cattle

2026-08-31

Abstract excerpt

<title>Abstract</title> <p>Traditional short-read RNA-seq lacks the resolution to fully capture full-length isoforms and complex alternative splicing, leaving a "missing regulation" gap in existing molecular atlases. Here, we present a population-scale, multi-omics dissection of bovine complex traits using matched deep whole-genome sequencing (30×), long-read (ONT) and short-read RNA-seq, as well as metabolome da...

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Literature Corpus work
c1fd4cf4-6f47-5634-8b64-014dc1df0e31
DOI
10.21203/rs.3.rs-9924044/v1
Open publication

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Long-read RNA-seq resolves isoform-level and context-specific regulatory architecture of complex traits in cattleDOI 10.21203/rs.3.rs-9924044/v1
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