Article

Long-read RNA-seq resolves isoform-level and context-specific regulatory architecture of complex traits in cattle

2026-06-05

Abstract excerpt

Traditional short-read RNA-seq lacks the resolution to fully capture full-length isoforms and complex alternative splicing, leaving a "missing regulation" gap in existing molecular atlases. Here, we present a population-scale, multi-omics dissection of bovine complex traits using matched deep whole-genome sequencing (30×), long-read (ONT) and short-read RNA-seq, as well as metabolome data from 432 dairy cows acros...

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Literature Corpus work: ed5557ce-2781-56b2-8bbe-46db3c126a70
DOI: 10.64898/2026.06.04.730050

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