Article
Comparative transcriptome in large-scale human and cattle populations.
Genome biology - 22 Aug 2022
Yao Yuelin, Liu Shuli, Xia Charley, Gao Yahui, Pan Zhangyuan, Canela-Xandri Oriol, Khamseh Ava, Rawlik Konrad, Wang Sheng, Li Bingjie, Zhang Yi, Pairo-Castineira Erola, D'Mellow Kenton, Li Xiujin, Yan Ze, Li Cong-Jun, Yu Ying, Zhang Shengli, Ma Li, Cole John B, Ross Pablo J, Zhou Huaijun, Haley Chris, Liu George E, Fang Lingzhao, Tenesa Albert
Abstract excerpt
BACKGROUND: Cross-species comparison of transcriptomes is important for elucidating evolutionary molecular mechanisms underpinning phenotypic variation between and within species, yet to date it has been essentially limited to model organisms with relatively small sample sizes. RESULTS: Here, we systematically analyze and compare 10,830 and 4866 publicly available RNA-seq samples in humans and cattle,...
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