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A multi-tissue atlas of regulatory variants in cattle.

Nature genetics - 1 Sept 2022

Liu Shuli, Gao Yahui, Canela-Xandri Oriol, Wang Sheng, Yu Ying, Cai Wentao, Li Bingjie, Xiang Ruidong, Chamberlain Amanda J, Pairo-Castineira Erola, D'Mellow Kenton, Rawlik Konrad, Xia Charley, Yao Yuelin, Navarro Pau, Rocha Dominique, Li Xiujin, Yan Ze, Li Congjun, Rosen Benjamin D, Van Tassell Curtis P, Vanraden Paul M, Zhang Shengli, Ma Li, Cole John B, Liu George E, Tenesa Albert, Fang Lingzhao

Abstract excerpt

Characterization of genetic regulatory variants acting on livestock gene expression is essential for interpreting the molecular mechanisms underlying traits of economic value and for increasing the rate of genetic gain through artificial selection. Here we build a Cattle Genotype-Tissue Expression atlas (CattleGTEx) as part of the pilot phase of the Farm animal GTEx (FarmGTEx) project for the research community...

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Cattle
Gene Expression Regulation
Phenotype
Quantitative Trait Loci

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Analysis, RNA

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PMID: 35953587
DOI: 10.1038/s41588-022-01153-5
PMCID: PMC7613894

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