Article

Identification of a Distinct Metabolomic Subtype of Sporadic ALS Patients

2018-09-13

Abstract excerpt

Sporadic amyotrophic lateral sclerosis (sALS) is a progressive motor neuron disease resulting in paralysis and death. Genes responsible for familial ALS have been identified, however the molecular basis for sALS is unknown. To discover metabotypic biomarkers that inform on disease etiology, untargeted metabolite profiling was performed on 77 patient-derived dermal fibroblast lines and 45 age/sex-matched controls....

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Literature Corpus work: c1fb1d8c-365d-5e66-9f99-ab5f58d7a0d3
DOI: 10.1101/416396

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