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Article

Abnormal energy metabolism in ALS: a key player?

19 Jun 2023

Abstract excerpt

PURPOSE OF THE REVIEW: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease of the motor system due to the selective and progressive degeneration of both upper and lower motor neurons. Disturbances in energy homeostasis were repeatedly associated with the ALS pathogenesis and appear early during the disease process. In this review, we highlight recent work demonstrating the crucial role...

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PMID: 37338894
DOI: 10.1097/wco.0000000000001164

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