Article

Gene Expression Profiles in Sporadic ALS Fibroblasts Define Disease Subtypes and The Metabolic Effects of the Investigational Drug EH301

2021-10-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Majority of ALS cases are sporadic (sALS), as they lack defined genetic causes. Metabolic alterations shared between the nervous system and skin fibroblasts have emerged in ALS. Recently, we found that a subgroup of sALS fibroblasts (sALS1) is characterized by metabolic profiles (metabotype) distinct from other sALS cases (sALS2) and controls, suggesting that me...

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Literature Corpus work: 91fffbb9-a00d-5006-b304-ff5e05913407
DOI: 10.21203/rs.3.rs-952505/v1

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Gene Expression Profiles in Sporadic ALS Fibroblasts Define Disease Subtypes and The Metabolic Effects of the Investigational Drug EH301DOI 10.21203/rs.3.rs-952505/v1Read

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