Article

The human canonical core histone catalogue

2019-07-30

Abstract excerpt

Core histone proteins H2A, H2B, H3, and H4 are encoded by a large family of genes distributed across the human genome. Canonical core histones contribute the majority of proteins to bulk chromatin packaging, and are encoded in 4 clusters by 65 coding genes comprising 17 for H2A, 18 for H2B, 15 for H3, and 15 for H4, along with at least 17 total pseudogenes. The canonical core histone genes display coding variation...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c1e79690-96cf-5e6e-8184-a4539c805665
DOI: 10.1101/720235

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The human canonical core histone catalogueDOI 10.1101/720235Read

Histone variants: nuclear function and disease.Semantic proximity Read

The human histone H3 complement anno 2011.Semantic proximity Read

The Histone Database.Semantic proximity Read

HistoneDB 2.0: a histone database with variants--an integrated resource to explore histones and their variants.Semantic proximity Read

Short Histone H2A Variants: Small in Stature but not in Function.Semantic proximity Read

Towards understanding the regulation of histone H1 somatic subtypes with OMICsSemantic proximity Read

Novel classes and evolutionary turnover of histone H2B variants in the mammalian germlineSemantic proximity Read

A common classification framework for histone sequence alterations in tumours: an expert consensus proposal.Semantic proximity Read

Histone variants--ancient wrap artists of the epigenome.Semantic proximity Read

Large-scale determination and characterization of cell type-specific regulatory elements in the human genomeSemantic proximity Read

Histone variants and transcription regulation.Semantic proximity Read

Solid tumours hijack the histone variant network.Semantic proximity Read