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Article

A common classification framework for histone sequence alterations in tumours: an expert consensus proposal.

The Journal of pathology - 1 Jun 2021

Leske Henning, Dalgleish Raymond, Lazar Alexander J, Reifenberger Guido, Cree Ian A

Abstract excerpt

The description of genetic alterations in tumours is of increasing importance. In human genetics, and in pathology reports, sequence alterations are given using the human genome variation society (HGVS) guidelines for the description of such variants. However, there is less adherence to these guidelines for sequence variations in histone genes. Due to early cleavage of the N-terminal methionine in most histones,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33779999
DOI: 10.1002/path.5666

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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