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Article

The human histone H3 complement anno 2011.

Biochimica et biophysica acta - 1 Oct 2011

Ederveen Thomas H A, Mandemaker Imke K, Logie Colin

Abstract excerpt

Histones are highly basic, relatively small proteins that complex with DNA to form higher order structures that underlie chromosome topology. Of the four core histones H2A, H2B, H3 and H4, it is H3 that is most heavily modified at the post-translational level. The human genome harbours 16 annotated bona fide histone H3 genes which code for four H3 protein variants. In 2010, two novel histone H3.3 protein variants...

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PMID: 21782046
DOI: 10.1016/j.bbagrm.2011.07.002

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