Histone variants: nuclear function and disease.

Abstract excerpt

Histone variants have emerged as important contributors to the regulation of chromatin structure and therefore of almost all DNA-based processes. Hence, these specialized proteins play important roles in transcriptional regulation, cell cycle progression, DNA repair, chromatin stability, chromosome segregation and apoptosis. Due to their evident biological significance, it is not surprising that mutations or the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chromatin
• Share to Chromosome Segregation
• Share to DNA