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Selective whole-genome sequencing of <i>Plasmodium</i> parasites directly from blood samples by Nanopore adaptive sampling

2022-11-29

Abstract excerpt

<h4>Background</h4> Whole-genome sequencing (WGS) is becoming an increasingly popular tool to study the population genetics and drug resistance of Plasmodium spp. However, the predominance of human DNA in a malaria patient blood sample requires time-consuming lab procedures to filter out human DNA or enrich Plasmodium DNA. Here, we investigated the potential of adaptive sampling to enrich for Plasmodium DNA wh...

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Literature Corpus work
c1e545d0-e412-57ea-bdf7-03d69689137c
DOI
10.1101/2022.11.29.518068
Open publication

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Selective whole-genome sequencing of <i>Plasmodium</i> parasites directly from blood samples by Nanopore adaptive samplingDOI 10.1101/2022.11.29.518068
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