Article

5WBF: A low-cost and straightforward whole blood filtration method suitable for whole-genome sequencing of <i>Plasmodium falciparum</i> clinical isolates

2021-08-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Whole-genome sequencing (WGS) is becoming increasingly helpful to assist malaria control programs. A major drawback of this approach is the large amount of human DNA compared to parasite DNA extracted from unprocessed whole blood. As red blood cells (RBCs) have a diameter of about 7-8 μm and exhibit some deformability, we hypothesized that cheap and commercially available 5...

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Literature Corpus work: f7b995f4-4f41-5fad-8c2d-64637c75e007
DOI: 10.1101/2021.08.30.457783

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