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Article

Selective whole genome amplification of Plasmodium malariae DNA from clinical samples reveals insights into population structure.

Scientific reports - 2 Jul 2020

Ibrahim Amy, Diez Benavente Ernest, Nolder Debbie, Proux Stephane, Higgins Matthew, Muwanguzi Julian, Gomez Gonzalez Paula Josefina, Fuehrer Hans-Peter, Roper Cally, Nosten Francois, Sutherland Colin, Clark Taane G, Campino Susana

Abstract excerpt

The genomic diversity of Plasmodium malariae malaria parasites is understudied, partly because infected individuals tend to present with low parasite densities, leading to difficulties in obtaining sufficient parasite DNA for genome analysis. Selective whole genome amplification (SWGA) increases the relative levels of pathogen DNA in a clinical sample, but has not been adapted for P. malariae parasites. Here we...

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Identifiers

PMID: 32616738
DOI: 10.1038/s41598-020-67568-4
PMCID: PMC7331648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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