Article

Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior

2017-09-12

Abstract excerpt

<h4>Background</h4> Smoking and alcohol use behaviors in humans have been associated with common genetic variants within multiple genomic loci. Investigation of rare variation within these loci holds promise for identifying causal variants impacting biological mechanisms in the etiology of disordered behavior. Microarrays have been designed to genotype rare nonsynonymous and putative loss of function variants. Su...

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Literature Corpus work: c1b3f055-ba38-55ed-bebb-3cb813581b39
DOI: 10.1101/187658

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