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Article

Genetic variation in the exome: Associations with alcohol and tobacco co-use.

Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors - 1 May 2017

Otto Jacqueline M, Gizer Ian R, Ellingson Jarrod M, Wilhelmsen Kirk C

Abstract excerpt

Shared genetic factors represent one underlying mechanism thought to contribute to high rates of alcohol and tobacco co-use and dependence. Common variants identified by molecular genetic studies tend to confer only small disease risk, and rare protein-coding variants are posited to contribute to disease risk, as well. However, given that genotyping technologies allowing for their inclusion in association studies...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28368157
DOI: 10.1037/adb0000270
PMCID: PMC5466882

Genes

CHRNA3
CHRNA5
CHRNB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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