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Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice

2023-01-05

Abstract excerpt

Aging is a complex process best characterized as the chronic dysregulation of cellular processes leading to deteriorated tissue and organ function. While aging cannot currently be prevented, its impact on lifespan and healthspan in the elderly can potentially be minimized by interventions that aim to return these cellular processes to optimal function. Recent studies have demonstrated that partial reprogramming us...

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Literature Corpus work
c1983c04-fbc5-5cb1-870e-d0d0bab9d800
DOI
10.1101/2023.01.04.522507
Open publication

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Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged MiceDOI 10.1101/2023.01.04.522507
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